Issues with Current Topical Ocular Drug Therapies
- An overdose in each drop
- Administration Errors
- Frequent Contamination
- Discontinuation Rates
- Poor Outcomes
~5x the necessary drug
Each drop delivers ~5x the necessary drug
Patients often double-dose due to uncertainty. 1
1. Marshall Allen. (2017, October 18). Drug Companies Make Eyedrops Too Big — And You Pay for the Waste. Retrieved from https://www.propublica.org/article/drug-companies-make-eyedrops-too-big-and-you-pay-for-the-waste
> 90% of patients dose improperly
30% of patients who think they have
good technique actually miss the eye. 2
2. A.J. Winfield, D. Jessiman et al. A study of the causes of non-compliance by patients prescribed eyedrops.. Br.J.. Ophthal.1990 Aug;74(8):477-480; Online Medicine (Baltimore), 2015; 94(8):e583
24% of self-administered bottles
are found to be contaminated. 3
3. B. Teucher, J. Wagner, et al. Microbial contamination of glaucoma eye drops used by patients compared with ocular medications used in the hospital;
51% of patients discontinue
their topical medical therapy
within 1 year. 4
4. A.P. Rotchford, K.M. Murphy. Compliance with Timolol treatment in glaucoma. Eye, 1998; 12:234-6;
Poor administration & compliance
lead to poor outcomes.
Aiming to Improve Patient Outcomes
Novel
Approach for
Drug Delivery
Up to 80% dose reduction shown to have comparable efficacy and potentially reduced adverse events.
Precision
Delivery Using a
Lower Dose
Accurate & precise delivery of drug in a low-cost platform well suited for the topical ophthalmic market.
Potential Benefits
for Patients,
Physicians & Providers
Potential for more comfort and convenience, fewer side effects and reduced burden on healthcare system.
